The latest VirtualBox v5.2.8 version crashes your host system (i.e. BSOD on your Windows system) when booting to an E2B USB drive.
If you use VBox to test booting of E2B then please install v5.2.4 or 5.2.6 instead, but do not update to 5.2.8.
I discovered this several days ago (I thought it may have been just my system), but it has now been confirmed by another user.
http://www.easy2boot.com/forum/
[Edit: I have re-released E2B v1.98 2018-03-09 which should prevent the BSOD with VBOX from occurring. Please download the latest version of E2B and update your E2B drives if you want to use VBOX 5.2.8]
If you use VBox to test booting of E2B then please install v5.2.4 or 5.2.6 instead, but do not update to 5.2.8.
I discovered this several days ago (I thought it may have been just my system), but it has now been confirmed by another user.
http://www.easy2boot.com/forum/
[Edit: I have re-released E2B v1.98 2018-03-09 which should prevent the BSOD with VBOX from occurring. Please download the latest version of E2B and update your E2B drives if you want to use VBOX 5.2.8]